Outlook for Mac works with Microsoft Exchange, Office 365, (including Hotmail and MSN), Gmail, Yahoo Mail, and iCloud Learn more about Office 365 Office 365 is a cloud-based subscription service that brings together premium versions of Word, Excel, PowerPoint, Outlook and OneDrive, with the best tools for the way people work today. You’ll have Office applications on your Mac or PC, apps on tablets and smartphones for when you're on the go, and Office Online on the web for everywhere in between. Office 365 customers get the new Office for Mac first.